Clinical, Toxicological, Biochemical, and Hematologic Parameters in Lead Exposed Workers of a Car Battery Industry

Authors

  • Bita Dadpour Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mahdi Balali-Mood Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mahmoud Sadeghi Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mohammad Taghi Shakeri Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Seyed Reza Mousavi Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Sina Kianoush Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Valiollah Moradi Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:

Background: Lead is a toxic element which causes acute, subacute or chronic poisoning through environmental and occupational exposure. The aim of this study was to investigate clinical and laboratory abnormalities of chronic lead poisoning among workers of a car battery industry. Methods: Questionnaires and forms were designed and used to record demographic data, past medical histories and clinical manifestations of lead poisoning. Blood samples were taken to determine biochemical (using Auto Analyzer; Model BT3000) and hematologic (using Cell Counter Sysmex; Model KX21N) parameters. An atomic absorption spectrometer (Perkin-Elmer, Model 3030, USA) was used to determine lead concentration in blood and urine by heated graphite atomization technique. Results: A total of 112 men mean age 28.78±5.17 years, who worked in a car battery industry were recruited in the present study. The most common signs/symptoms of lead poisoning included increased excitability 41.9%, arthralgia 41.0%, fatigue 40.1%, dental grey discoloration 44.6%, lead line 24.1%, increased deep tendon reflexes (DTR) 22.3%, and decreased DTR (18.7%). Blood lead concentration (BLC) was 398.95 µg/L±177.40, which was significantly correlated with duration of work (P=0.044) but not with the clinical manifestations of lead poisoning. However, BLC was significantly correlated with urine lead concentration (83.67 µg/L±49.78; r2=0.711; P

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

clinical, toxicological, biochemical, and hematologic parameters in lead exposed workers of a car battery industry

background: lead is a toxic element which causes acute, subacute or chronic poisoning through environmental and occupational exposure. the aim of this study was to investigate clinical and laboratory abnormalities of chronic lead poisoning among workers of a car battery industry. methods: questionnaires and forms were designed and used to record demographic data, past medical histories and clin...

full text

Clinical and Laboratory Findings of Lead Hepatotoxicity in the Workers of a Car Battery Manufacturing Factory

Background: Occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. Several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. This study was designed to investigate the clinical manifestations and pathological parameters of h...

full text

The Relationship between Blood Lead Level and Neuro-psychological and Hematological Findings in Lead-Exposed Workers of Battery Industry

Background: Hematological effects and digestive and neuro-psychological signs and symptoms are some manifestations of lead toxicity. However, there are conflicting reports of their prevalence among lead exposed workers and their relationship with blood lead levels (BLL). This case- control study assessed the relationship between BLL and hematological indexes and digestive (abdominal colic, ir...

full text

clinical and laboratory findings of lead hepatotoxicity in the workers of a car battery manufacturing factory

background: occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. this study was designed to investigate the clinical manifestations and pathological parameters of h...

full text

the relationship between blood lead level and neuro-psychological and hematological findings in lead-exposed workers of battery industry

background: hematological effects and digestive and neuro-psychological signs and symptoms are some manifestations of lead toxicity. however, there are conflicting reports of their prevalence among lead exposed workers and their relationship with blood lead levels (bll). this case- control study assessed the relationship between bll and hematological indexes and digestive (abdominal colic, iron...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 38  issue 1

pages  30- 37

publication date 2013-03-01

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023